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FIELD OF INVENTION
The invention relates to novel paclitaxel derivatives useful in the treatment of cancer. More specifically, the invention relates to paclitaxel derivatives obtained by substitutions at the C.sub.2', C.sub.3' and/or C.sub.7 positions. The invention also provides pharmaceutical
BACKGROUND OF THE INVENTION
Introduction
The present invention relates to purified drug resistant tumor cells, mutated polynucleotide sequences which confer drug resistance, an assay for detecting drug resistant tumor cells in mammals including human, reagents specific for PCR enhancement of mutant
BACKGROUND OF THE INVENTION
Virtually all of the many antineoplastic drugs that are currently used in the treatment of cancer have very serious and harmful side effects. This is because cancer is generally treated with medications that interfere with the growth of rapidly dividing cells. Such
BACKGROUND OF THE INVENTION
Virtually all of the many antineoplastic drugs that are currently used in the treatment of cancer have very serious and harmful side effects. This is because cancer is generally treated with medications that interfere with the growth of rapidly dividing cells. Such
BACKGROUND OF THE INVENTION
Virtually all of the many antineoplastic drugs that are currently used in the treatment of cancer have very serious and harmful side effects. This is because cancer is generally treated with medications that interfere with the growth of rapidly dividing cells. Such
CROSS REFEREBCE TO RELATED APPLICATIONS
This application is a United States Application filed under 35 U.S.C..sctn.371 claiming benefit to PCT Application No. PCT/IB2009/050677, filed on Feb. 19, 2009, which claims the benefit of PCT Application No. PCT/IB2008/050607, filed on Feb. 20, 2008.
The
FIELD OF THE INVENTION
This invention pertains to the use of veliparib in combination with carboplatin and paclitaxel in the treatment of smokers with non-small cell lung cancer.
BACKGROUND OF THE INVENTION
Lung cancer accounts for more deaths than any other cancer in both men and women. An
BACKGROUND
1. Technical Field
This document relates to methods and materials involved in treating cancer (e.g., skin cancers such as melanoma). For example, this document relates to methods and materials involved in using complexes containing albumin-containing nanoparticles (e.g., ABRAXANE.RTM.
BACKGROUND
1. Technical Field
This document relates to methods and materials involved in treating cancer (e.g., skin cancers such as melanoma). For example, this document relates to methods and materials involved in using complexes containing albumin-containing nanoparticles (e.g., ABRAXANE.RTM.
BACKGROUND
1. Technical Field
This document relates to methods and materials involved in treating cancer (e.g., skin cancers such as melanoma). For example, this document relates to methods and materials involved in using complexes containing albumin-containing nanoparticles (e.g., ABRAXANE.RTM.
The invention relates to a method for the treatment of tumors sensitive to Paclitaxel, and more particularly concerns a method by which a significant remission or cure of the tumor, with very low toxic side effects, can be achieved by just a few infusions, each of short duration and spaced apart by
BACKGROUND
1. Technical Field
This document relates to methods and materials involved in treating cancer (e.g., skin cancers such as melanoma). For example, this document relates to methods and materials involved in using complexes containing albumin-containing nanoparticles (e.g., ABRAXANE.RTM.
BACKGROUND
1. Technical Field
This document relates to methods and materials involved in treating cancer (e.g., skin cancers such as melanoma). For example, this document relates to methods and materials involved in using complexes containing albumin-containing nanoparticles (e.g., ABRAXANE.RTM.
BACKGROUND
1. Technical Field
This document relates to methods and materials involved in treating cancer (e.g., skin cancers such as melanoma). For example, this document relates to methods and materials involved in using complexes containing albumin-containing nanoparticles (e.g., ABRAXANE.RTM.
BACKGROUND
1. Technical Field
This document relates to methods and materials involved in treating cancer (e.g., skin cancers such as melanoma). For example, this document relates to methods and materials involved in using complexes containing albumin-containing nanoparticles (e.g., ABRAXANE.RTM.