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physalin d/physalis
Ο σύνδεσμος αποθηκεύεται στο πρόχειρο
13 Αποτελέσματα
Antimicrobial activity of the extracts and physalin D from Physalis alkekengi and evaluation of antioxidant potential of physalin D.
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Σύνδεση εγγραφή
Physalis alkekengi L. (Solanaceae) is a popular plant in traditional European and Chinese folk medicine, and it has been reported to have many ethnopharmacological properties including antifungal, anti-cough, anti-inflammatory, analgesic, and febricide activities. Some active components from
Isolation and quantitative analysis of physalin D in the fruit and calyx of Physalis alkekengi L.
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Σύνδεση εγγραφή
Physalin D was isolated from the methanol extract of Physalis alkekengi L. fruits by combination of different chromatographic methods (CPC, TLC, HPLC). The structure was elucidated based on 1H and 13C NMR spectral analysis with the aid of 2D-correlation spectroscopy (1H, 1H-COSY, HSQC and HMBC) and
Comparative Metabolomic and Proteomic Analyses Reveal the Regulation Mechanism Underlying MeJA-Induced Bioactive Compound Accumulation in Cutleaf Groundcherry ( Physalis angulata L.) Hairy Roots.
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Σύνδεση εγγραφή
Cutleaf groundcherry ( Physalis angulata L.) is an annual plant with a number of medicinal ingredients. However, studies about the secondary metabolism of P. angulata are very limited. An integrated metabolome and proteome approach was used to reveal the variations in the metabolism associated with
Chemopreventive Agents from Physalis minima Function as Michael Reaction Acceptors.
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Σύνδεση εγγραφή
BACKGROUND
The fruits of some varieties of genus Physalis have been used as delicious fruits and functional food in the Northeast of China.
METHODS
To reveal the functional material basis, we performed bioactivity-guided phytochemical research and chemopreventive effect assay of the constituents
Antitumor agent, physalin F from Physalis angulata L.
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Σύνδεση εγγραφή
Physalin F and physalin D were isolated and characterized from the ethanolic extract of the whole plant of Physalis angulata L. (Solanaceae). Systematic fractionation of the ethanolic extract of the plant led to characterization of physalin F from the fraction PAIV-2 as an active ingredient which
In-vitro and in-vivo antitumour activity of physalins B and D from Physalis angulata.
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Σύνδεση εγγραφή
We have evaluated the in-vitro and in-vivo antitumour activity of physalin B and physalin D isolated from the aerial parts of Physalis angulata. In-vitro, both compounds displayed considerable cytotoxicity against several cancer cell lines, showing IC50 values in the range of 0.58 to 15.18 microg
Isolation, structures, and structure - cytotoxic activity relationships of withanolides and physalins from Physalis angulata.
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Σύνδεση εγγραφή
Phytochemical investigation of Physalis angulata was initiated following primary biological screening. Fractionation of CHCl3 and n-BuOH solubles of the MeOH extract from the whole plant was guided by in vitro cytotoxic activity assay using cultured HONE-1 and NUGC cells and led to the isolation of
Antimycobacterial physalins from Physalis angulata L. (Solanaceae).
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Σύνδεση εγγραφή
Crude extracts and fractions from aerial parts of Physalis angulata have been bioassayed for antimycobacterial activity. Fraction A1-29-12 containing physalins B, F and D exhibited a minimum inhibitory concentration value (MIC) against Mycobacterium tuberculosis H(37)Rv strain of 32 microg/mL.
An ultra-pressure liquid chromatography-tandem mass spectrometry method for the simultaneous determination of three physalins in rat plasma and its application to pharmacokinetic study of Physalis alkekengi var. franchetii (Chinese lantern) in rats.
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Σύνδεση εγγραφή
An ultra-high pressure liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method was developed for the quantification of three major ingredients in Chinese lantern preparations (CLP) in rat plasma. Following extraction by ethyl acetate, the analytes were separated on an Acquity UPLC BEH
The structure of physalin T from Physalis alkekengi var. franchetti.
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Σύνδεση εγγραφή
A new steroidal constituent named physalin T (3) was isolated from the aqueous extract of Physalis alkekengi var. francheti. Based on 1H and 13C NMR spectral studies the structure was assigned as 2,3-dihydrophysalin D, i.e., 5alpha,6beta-dihydroxy-2,3,5,6-tetrahydrophysalin B, which is the first
In vivo effects on the intestinal microflora of Physalis alkekengi var. francheti extracts.
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Σύνδεση εγγραφή
This study aimed to investigate the effects on the intestinal microflora balance of Physalis alkekengi var. francheti extracts (PE) using in vivo mouse model. Luteolin-7-O-β-glycoside, Physalin J, Physalin D, and Physalin P were isolated from PE extracts and identified. Bacteroides, Lactobacillus,
LC-MS/MS method for simultaneous determination of flavonoids and physalins in rat plasma: Application to pharmacokinetic study after oral administration of Physalis alkekengi var. franchetii (Chinese lantern) extract.
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Σύνδεση εγγραφή
A rapid and sensitive liquid chromatography with tandem mass spectrometry (LC-MS/MS) method was developed and validated for the simultaneous determination of luteolin, luteolin-7-O-β-D-glucopyranoside, physalin A, physalin D and physalin L in rat plasma. Scutellarein and dexamethasone were used as
Immune depression in Rhodnius prolixus by seco-steroids, physalins.
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Σύνδεση εγγραφή
A comparative study of the effects of physalins, seco-steroidal substances of Physalis angulata (Solanaceae), on the immune reactions of R. prolixus was carried out. Ecdysis and mortality were not affected by treatment with physalins B, D, F or G (1-10 microg/ml of blood meal). R. prolixus larvae
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