5 Αποτελέσματα
Four novel asymmetrical diarylethenes with a pyrrole and a variable aryl unit have been synthesized. Their crystal structures and photochromic performance were systematically studied to elucidate the effects of the aromatic stabilization energy (ASE) of aryl units. Experimental results showed that
Two new asymmetric isomeric diarylethenes having pyrrole and thiophene units have been synthesized by one-pot reaction and characterized by single crystal X-ray diffraction analysis. The two prepared diarylethenes had disparate crystal structures, and they exhibited distinctly different photochromic
Aggregation-induced emission luminogens (AIEgens) have attracted extensive interest for their outstanding luminescence properties in the aggregated state and even in the solid state. In this work, we developed a series of novel AIEgens based on
Although diarylethene derivatives are considered to undergo thermally irreversible photochromic reactions, this is not always the case. Here, we report on thermally reversible photochromic diarylethenes having pyrrole-2-carbonitrile aryl groups. The thermal stability of the coloured closed-ring
Background: M4112 is an oral, potent, and selective indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase 2 (TDO2) dual inhibitor. Here, we report preclinical data and first-in-human phase I data, including safety,