Avastin as an Adjunct to Diode Laser in the Treatment of Neovascular Glaucoma
Keywords
Abstract
Description
Design: Prospective, comparative interventional case series. Method: Patients were randomly assigned into Group A which were treated with Diode laser cyclophotocoagulation alone, whereas group B received intravitreal Avastin (One milligram = 0.04mL of 25 mg/mL) in conjunction with the Diode Laser. The preoperative data included etiology, mean age; follow up period, and a full ophthalmological examination with emphasis on mean IOP, iris neovascularization, pain and corneal edema.
Dates
| Last Verified: | 11/30/2007 |
| First Submitted: | 01/06/2010 |
| Estimated Enrollment Submitted: | 01/14/2010 |
| First Posted: | 01/17/2010 |
| Last Update Submitted: | 01/14/2010 |
| Last Update Posted: | 01/17/2010 |
| Actual Study Start Date: | 12/31/2005 |
| Estimated Primary Completion Date: | 03/31/2008 |
| Estimated Study Completion Date: | 03/31/2008 |
Condition or disease
Intervention/treatment
Procedure: Diode laser cyclophotocoagulation enhanced by intravitreal injection of Avastin
Phase
Arm Groups
| Arm | Intervention/treatment |
|---|---|
| Experimental: Avastin , diode laser cyclophotcoagulation Intravitreal Avastin injection in conjunction with diode laser cyclophotocoagulation | |
| Active Comparator: Diode Laser cyclophotocoagulation Diode laser cyclophotocoagulation to control intraocular pressure |
Eligibility Criteria
| Ages Eligible for Study | 14 Years To 14 Years |
| Sexes Eligible for Study | All |
| Accepts Healthy Volunteers | Yes |
| Criteria | Inclusion Criteria: - Neovascular absolute glaucoma - Painful blind eyes Exclusion Criteria: - Neovascular glaucoma with useful vision or potential for useful vision |
Outcome
Primary Outcome Measures
1. Disappearance of iris neovessels [2 weeks]
Secondary Outcome Measures
1. Intra ocular pressure [4 weeks]
