Obstructive Sleep Apnoea in Patients With Intermittent Claudication
Keywords
Abstract
Description
In patients with peripheral artery disease (PAD), exercise induced limb ischemia (claudication) which limits walking capacity. Symptoms are due to pain at hip and/or buttock. Couple of origins may induce this pain such as vascular, cardiac, respiratory, musculoskeletal, neurologic, hematologic etc. The rate of associated respiratory pathology to patients with lower extremity artery disease (LEAD) is around 15%. The intolerance to walk could be link to an exercise hypoxia which appears with lower limb pain with or without associated dyspnea. The exercise hypoxemia becomes a diagnostic for an intermittent vascular claudication. Tests which are performed to diagnose an intermittent claudication are the Ankle to Brachial Systolic pressure Index (ABI), the echo-Doppler of lower limb arteries and the walking test on a treadmill associated to a measurement of the distal and chest transcutaneous oxygen pressure (tcpO2).
Thus, the purpose of the present research is to determine the prevalence of obstructive sleep apnoea in patient with PAD.
Dates
| Last Verified: | 01/31/2016 |
| First Submitted: | 02/17/2013 |
| Estimated Enrollment Submitted: | 02/25/2013 |
| First Posted: | 02/28/2013 |
| Last Update Submitted: | 10/29/2017 |
| Last Update Posted: | 10/31/2017 |
| Actual Study Start Date: | 05/02/2013 |
| Estimated Primary Completion Date: | 10/12/2017 |
| Estimated Study Completion Date: | 10/12/2017 |
Condition or disease
Phase
Eligibility Criteria
| Ages Eligible for Study | 18 Years To 18 Years |
| Sexes Eligible for Study | All |
| Sampling method | Probability Sample |
| Accepts Healthy Volunteers | Yes |
| Criteria | Inclusion Criteria: - Register to the social health insurance - Referred for a walk test because of claudication - Maximal walking ditance < 750m - Older than 18 years old - Able to understand the protocol of the study Exclusion Criteria: - Cardiac insufficiency already known, stage III or IV i.e. dyspnea at rest Unstable angina or myocardial infarction within the previous three months inclusion - Severe reparatory disease already known - Parkinson disease, hémiplégia ou paraplégia - Does not want to participate to the protocol - Pregnant women - Adults to enhanced protection, deprived of their liberty by judicial or administrative authority, without consent hospitalized or admitted to a health facility or social purposes other than research - Being in a period of exclusion from another biomedical study |
Outcome
Primary Outcome Measures
1. Prevalence of an Apnea hyponea index > 15 [up to 2 months after inclusion]
