Role of Ginkgo Biloba Extract in IUGR
Keywords
Abstract
Dates
Last Verified: | 02/29/2016 |
First Submitted: | 04/20/2015 |
Estimated Enrollment Submitted: | 04/22/2015 |
First Posted: | 04/23/2015 |
Last Update Submitted: | 03/19/2016 |
Last Update Posted: | 03/21/2016 |
Actual Study Start Date: | 04/30/2014 |
Estimated Primary Completion Date: | 09/30/2015 |
Estimated Study Completion Date: | 11/30/2015 |
Condition or disease
Intervention/treatment
Drug: Ginkgo Biloba Extract group
Other: Placebo group
Phase
Arm Groups
Arm | Intervention/treatment |
---|---|
Active Comparator: Ginkgo Biloba Extract group This group received Ginko Biloba, two tablets per day | Drug: Ginkgo Biloba Extract group |
Placebo Comparator: Placebo group This group received placebo two tablets per day . | Other: Placebo group |
Eligibility Criteria
Ages Eligible for Study | 20 Years To 20 Years |
Sexes Eligible for Study | Female |
Accepts Healthy Volunteers | Yes |
Criteria | Inclusion Criteria: - Pregnant women in their third trimester (28-30 weeks of gestation). - Pregnant women whose pregnancy was complicated with intra uterine growth restriction (IUGR). - Normal Doppler indices in uterine, umbilical and middle cerebral arteries at time of recruitment. Exclusion Criteria: - Multiple pregnancies, - Hypertension, - Fetal congenital anomalies, - Previous history of congenital anomalies or chromosomal abnormalities. - Diabetes Mellitus - Premature pre-labor rupture of membranes - Antepartum hemorrhage |
Outcome
Primary Outcome Measures
1. Fetal weight (gm) [one and half year]
Secondary Outcome Measures
1. Doppler blood flow changes in uterine arteries indices [one and half year]
2. Doppler blood flow changes in umbilical arteries indices [one and half year]
3. Doppler blood flow changes in middle cerebral artery indices [one and half year]