The Incidence of Aphasia, Dysarthria and Dysphagia Following Stroke
Keywords
Abstract
Description
Study population:
Patients who are admitted to the acute Stroke Unit of the University Hospital Ghent will be recruited.
Study course:
The study has a prospective, observational design, with each participant receiving regular standard of care as follows: patients will undergo a clinical examination by a staff neurologists or the present attending in the emergency room. Tailored medical treatment will be given to each patient considering the type of stroke etc. as is standard of care (e.g. thrombolysis and/or thrombectomy for patients with ischemic stroke). Patients that are stable enough are transferred to the Stroke Unit where the neurologist or attending of the unit will reassess all stroke patients. NIHSS scores will be reported at least at day 2 +/- 1. A dysphagia screening is performed by the Stroke Unit nurses when the patient arrives at the Stroke Unit. The scores of the sub-items language and speech of the NIHSS and the dysphagia screening combined with a general screening by a speech language pathologist will be used to confirm or discard aphasia, dysphagia and dysarthria (incidence). When aphasia, dysarthria and/or dysphagia is confirmed, standardized tests will be performed. For this study, data of the following tests will be included for analysis: ScreeLing and/or BNT (aphasia), NSVO-Z and a perceptual assessment (dysarthria), MASA and/or the FOIS (dysphagia). At day 7 +/- 1, NIHSS scores will be reassessed (recovery in time). The diagnostic assessments and the NIHSS sub-items speech/language will be used to investigate the severity and recovery of the symptoms in time. Reports of the neurological clinical examination at follow-up will be retrospectively investigated if possible for additional information about recovery in time.
The total duration of data collection will be approximately 1 week and if possible three months follow-up.
Dates
| Last Verified: | 11/30/2019 |
| First Submitted: | 03/04/2018 |
| Estimated Enrollment Submitted: | 03/13/2018 |
| First Posted: | 03/20/2018 |
| Last Update Submitted: | 12/08/2019 |
| Last Update Posted: | 12/09/2019 |
| Actual Study Start Date: | 03/13/2018 |
| Estimated Primary Completion Date: | 10/03/2019 |
| Estimated Study Completion Date: | 10/03/2019 |
Condition or disease
Intervention/treatment
Diagnostic Test: Acute stroke patients
Phase
Arm Groups
| Arm | Intervention/treatment |
|---|---|
| Acute stroke patients All acute stroke patients will be screened for aphasia, dysarthria or dysphagia. When one of the symptoms is present, standardized assessments will follow to evaluate the severity. Recovery in time will be measured +/- 1 week following stroke. | Diagnostic Test: Acute stroke patients Screening (day 2 +/- 1; day 7 +/-1): NIHSS (National Health Institute Scale) 9 and 10 scores, dysphagia screening (nurse), speech-, and language screening (speech therapist)
Diagnostic assessment (day 2 +/-1-):
Dysphagia: MASA (Mann Assessment of Swallowing Abilities), FOIS (Functional Oral Intake Scale) Dysarthria: perceptual assessment, NSVO-Z (Nederlands spraakverstaanbaarheidsonderzoek - zinnen) Aphasia: ScreeLing, BNT (Boston Naming Test) |
Eligibility Criteria
| Sexes Eligible for Study | All |
| Sampling method | Probability Sample |
| Accepts Healthy Volunteers | Yes |
| Criteria | Inclusion Criteria: - Acute stroke patients admitted at the Acute Stroke Unit at the university hospital (Ghent) Exclusion Criteria: - Previous aphasia, dysarthria, dysphagia |
Outcome
Primary Outcome Measures
1. Incidence of aphasia [3 days]
Secondary Outcome Measures
1. Incidence of dysarthria [3 days]
2. Incidence of dysphagia [3 days]
3. Severity of aphasia (screening test) [3 days]
4. Severity of aphasia (naming test) [3 days]
5. severity of dysarthria (perceptual assessment) [3 days]
6. severity of dysarthria (comprehensibility test) [3 days]
7. severity of dysphagia (swallowing test) [3 days]
8. severity of dysphagia (oral intake) [3 days]
9. recovery of aphasia [1 week, 3 months]
10. recovery of dysarthria [1 week, 3 months]
