Effect of DCC on Neonatal Jaundice and Blood Gas Analysis in Infants Born to GDM Mothers
Keywords
Abstract
Dates
Last Verified: | 04/30/2020 |
First Submitted: | 04/26/2020 |
Estimated Enrollment Submitted: | 04/28/2020 |
First Posted: | 04/29/2020 |
Last Update Submitted: | 05/10/2020 |
Last Update Posted: | 05/12/2020 |
Actual Study Start Date: | 08/31/2019 |
Estimated Primary Completion Date: | 06/30/2020 |
Estimated Study Completion Date: | 08/31/2020 |
Condition or disease
Intervention/treatment
Procedure: delayed cord clamping
Procedure: early cord clamping
Phase
Arm Groups
Arm | Intervention/treatment |
---|---|
Experimental: delayed cord clamping clamping the cord at least 30s at birth | Procedure: delayed cord clamping umbilical cord clamping more than 30 seconds after birth |
Other: early cord clamping umbilical cord clamping before 15 seconds | Procedure: early cord clamping umbilical cord clamping within 15 seconds after birth |
Eligibility Criteria
Ages Eligible for Study | 18 Years To 18 Years |
Sexes Eligible for Study | Female |
Accepts Healthy Volunteers | Yes |
Criteria | Inclusion Criteria: People in the study should meet the following inclusion criteria: - Must be a singleton pregnancy - Clinical diagnosis of gestational diabetes mellitus according to ACOG Practice Bulletin Exclusion Criteria: - Pregnant women and neonates were excluded if they met the exclusion criteria (not included in if meeting one of following items ) - Maternal clinical diseases (hypertension disorders, abnormal liver function, Rhesus negative blood group or other blood system disease) - Maternal other pregnancy complications (polyhydramnios, oligohydramnios, placenta praevia, and abruptio placentae). - Delivery before 37 weeks or after 42 weeks - Neonatal weight was < 2.5 kg or>4.0 kg - Neonates had major congenital malformations (congenital anal atresia, congenital biliary atresia, congenital heart disease and so on, whether prenatal suspicion or diagnosis postpartum) - Neonatal septicemia, hemolytic disease or other diseases affecting bilirubin metabolism. |
Outcome
Primary Outcome Measures
1. neonatal transcutaneous bilirubin level [within the 1 to 3 days of age]
2. Number of infants with neonatal jaundice requiring phototherapy [within the 1 to 3 days of age]
3. Number of infants with neonatal hyperbilirubinemia [within the 1 to 3 days of age]
4. neonatal cord acid-base status [within the 15 minutes after delivery]
Secondary Outcome Measures
1. neonatal initial blood glucose levels [within the 30 minutes after delivery]