Effects of Progressive Relaxation Training in Breast Cancer Survivors Receiving Aromatatase Inhibitor Therapy
Keywords
Abstract
Description
Aromatase inhibitors (AI) can cause musculoskeletal problems and increased risk of fracture as side effects in breast cancer (BC) survivors. In particular, arthralgia can be observed in almost 50% of patients receiving AI. Moreover; cognitive dysfunctions , decreases in quality of life , anxiety and depression , sleep problems and fatigue can be seen in some of patients receiving AI. According to these possible side effects, evaluation and treatment of such health profiles, pain and symptoms is important in terms of improving the quality of life of the patients.
Progressive muscle relaxation exercises (PRE) were first described by Jacobson in 1938. PRE are in use today with different arrangements and updates. It was well defined physiological, perceptual and behavioral positive findings of muscle relaxation.(15) PRE was thought to be effective on artralgia, quality of life and anxiety in BC survivors receiving AI.
The patients have been founded from the medical records of oncology department of Florence Nightingale Hospital. Necessary permissions to use this data was provided from medical coordinator of the hospital and from the coordinator of Breast Cancer department.
Dates
| Last Verified: | 04/30/2020 |
| First Submitted: | 11/11/2019 |
| Estimated Enrollment Submitted: | 11/11/2019 |
| First Posted: | 11/14/2019 |
| Last Update Submitted: | 05/03/2020 |
| Last Update Posted: | 05/05/2020 |
| Actual Study Start Date: | 10/24/2019 |
| Estimated Primary Completion Date: | 07/31/2020 |
| Estimated Study Completion Date: | 08/31/2020 |
Condition or disease
Intervention/treatment
Other: Exercise Group
Phase
Arm Groups
| Arm | Intervention/treatment |
|---|---|
| Experimental: Exercise Group Progressive relaxation exercises (PRE) as 1 day supervised and 3 days home based program in a week, for 6 weeks | Other: Exercise Group Following intructions have been given to patients:
Punch your hands and contract your forearm
Punch your hands, push your elbow towards the seat
Bend your elbows
Push your shoulders back
Press your knee down and pull your toes towards you
Pull your knees towards you and push your feet down
Tighten your hips
Push your head back
Lift your eyebrows
Make wrinkles on your nose
Tighten your teeth
Push your chin down
Close your eyes and think of good things. |
| No Intervention: Control Group Information about pain and its treatment and the importance of relaxing exercises without any intervention.. |
Eligibility Criteria
| Ages Eligible for Study | 30 Years To 30 Years |
| Sexes Eligible for Study | Female |
| Accepts Healthy Volunteers | Yes |
| Criteria | Inclusion Criteria: - Using Aromatase Inhibitors for more than 6 months - Diagnosis of breast cancer stage 1-3 - Pain score ≥3 according to the Brief Pain Inventory Exclusion Criteria: - Participation on physical training in the previous 6 months period - Communication problems - Neurological or ortopedical problems - Presence of advanced lyphedema |
Outcome
Primary Outcome Measures
1. Brief pain inventory (BPI) [24 hours]
Secondary Outcome Measures
1. Functional Assessment of Chronic Illness Therapy - Breast (FACT-B) [7 days]
2. Hospital Anxiety and Depression scale (HAD) [7 days]
