Establishment of Squamous Cell Organoids of the Head and Neck to Assess Their Response to Innovative Therapies
Keywords
Abstract
Dates
Last Verified: | 01/31/2020 |
First Submitted: | 02/05/2020 |
Estimated Enrollment Submitted: | 02/05/2020 |
First Posted: | 02/06/2020 |
Last Update Submitted: | 07/07/2020 |
Last Update Posted: | 07/08/2020 |
Actual Study Start Date: | 07/02/2020 |
Estimated Primary Completion Date: | 01/31/2023 |
Estimated Study Completion Date: | 01/31/2025 |
Condition or disease
Intervention/treatment
Other: Constitution of tumor and blood samples
Phase
Eligibility Criteria
Ages Eligible for Study | 18 Years To 18 Years |
Sexes Eligible for Study | All |
Sampling method | Probability Sample |
Accepts Healthy Volunteers | Yes |
Criteria | Inclusion Criteria: - Patient over 18 years of age; - Patient with squamous cell carcinoma of the oral cavity, oropharynx, hypopharynx or larynx, classified T3Nx or T4Nx or T2N +, not previously treated; - Patient to be treated by surgery; - Patient affiliated to a social security scheme; - No opposition to participate in the study Exclusion Criteria: - Pregnant woman ; - Persons deprived of their liberty or under guardianship (including curatorship); - History of malignant pathology preceding inclusion (apart from basal cell carcinomas of the skin and carcinomas in situ of the cervix treated surgically) or concomitant at inclusion (synchronous tumor) |
Outcome
Primary Outcome Measures
1. Rate of establishment of exploitable organoids tumor [5 years]