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Jaundice as Initial Presentation of Liver Hydatidosis (ICTEHIDA)

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StatusActive, not recruiting
Sponsors
Universidad de Extremadura
Collaborators
Complejo Hospitalario Universitario de Badajoz

Keywords

Abstract

The aim of this study is to evaluate patients with hepatic hydatidosis whose symptom at diagnosis was obstructive jaundice. As well as analyzing, the rate of performing preoperative ERCP, the results after surgery and morbidity

Description

Retrospective study of patients operated on for liver hydatidosis and whose initial symptom was obstructive jaundice Study period: January 2006 to September 2018

The preoperative diagnosis was based on abdominal ultrasound (US), CT scan or magnetic nuclear resonance

Surgical technique Precautions are taken to avoid the spillage of the parasite in the abdominal cavity. The peritoneal cavity is liberally protected with scolicidal agents. All patients have intraoperative ultrasound. Ultrasound is performed to locate the presence of any cysts which might not be seen by the preoperative imaging. Intraoperative ultrasound is also used to find out the relation of the cyst to the big vessels. Depending on the intraoperative findings, the location and size of the cyst will be considered the type of surgery to be performed. Radical surgery (closed and open total cystopericystectomy, or liver resection) or conservative surgery (partial cystopericystectomy, removal of the vesicles with external or internal drainage). When the cyst affects a total lobe and / or the main pedicles, a hepatectomy is performed.

The demographic data of the patients will be taken from their clinical histories. It included age, sex, medical history of hidatidosis, clinical findings, laboratory data, radiological findings, endoscopic treatment, surgical treatment.

The investigators will analyze postoperative mortality and morbidity. Complications' ranking according to the Clavien-Dindo score, 'severe complication' is defined as greater or equal to IIIa

Follow-up The follow-up of these patients will be performed with ultrasound or CT and hydatid serology. The minimum follow-up of the patients is six months. Relapse is defined as the appearance of new active liver cysts after the patient had undergone surgery.

Dates

Last Verified: 01/31/2020
First Submitted: 02/11/2020
Estimated Enrollment Submitted: 02/11/2020
First Posted: 02/16/2020
Last Update Submitted: 02/12/2020
Last Update Posted: 02/16/2020
Actual Study Start Date: 12/31/2008
Estimated Primary Completion Date: 12/30/2018
Estimated Study Completion Date: 04/29/2020

Condition or disease

Hepatic Echinococcosis
Jaundice

Phase

-

Eligibility Criteria

Ages Eligible for Study 18 Years To 18 Years
Sexes Eligible for StudyAll
Sampling methodNon-Probability Sample
Accepts Healthy VolunteersYes
Criteria

Inclusion Criteria:

- Hepatic Hydatidosis with obstructive jaundice surgically treated

Exclusion Criteria:

- Patients with conservative treatment

Outcome

Primary Outcome Measures

1. Morbidity [90 days]

Postoperative morbidity after surgical treatment

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