Role of Functional Translation After Immersive Virtual Reality Exposure in Persons With Stroke
Keywords
Abstract
Description
Patients will be randomized to a control or experimental group. The experimental group will receive immersive VR training followed by the translation of related tasks in a real life environment. The control group will perform the same tasks in a real life environment but will receive immersive VR exposure to a non-related task.
Dates
| Last Verified: | 03/31/2020 |
| First Submitted: | 04/15/2020 |
| Estimated Enrollment Submitted: | 04/20/2020 |
| First Posted: | 04/23/2020 |
| Last Update Submitted: | 04/29/2020 |
| Last Update Posted: | 05/03/2020 |
| Actual Study Start Date: | 04/30/2020 |
| Estimated Primary Completion Date: | 04/30/2022 |
| Estimated Study Completion Date: | 04/30/2022 |
Condition or disease
Intervention/treatment
Other: Experimental
Other: Control
Phase
Arm Groups
| Arm | Intervention/treatment |
|---|---|
| Experimental: Experimental Virtual reality followed by translation into related functional tasks in a real life setting for 2 weeks + conventional therapies | Other: Experimental The experimental group will perform tasks in an immersive virtual reality setting designed to encourage functional task performance for 30 minutes. The patient will then be brought to a real-life setting and evaluated on similar task performances for an additional 30 minutes for a total of 60 minutes per day, 3 times a week for 2 weeks. |
| Active Comparator: Control Virtual reality followed by translation into non-related functional tasks in a real life setting for 2 weeks + conventional therapies | Other: Control The control group will also be asked to perform tasks in an immersive VR setting for 30 minutes, however tasks will be unrelated to the tasks performed in the real-life setting in the following 30 minutes. The control group will also receive 60 minutes of therapy a day, 3 times a week, for 2 weeks. |
Eligibility Criteria
| Ages Eligible for Study | 18 Years To 18 Years |
| Sexes Eligible for Study | All |
| Accepts Healthy Volunteers | Yes |
| Criteria | Inclusion Criteria: 1. 18-90 years old 2. Hospitalized at Loma Linda East Campus Rehabilitation Hospital 3. First time stroke patient 4. Upper limb hemiparesis 5. English-speaking 6. Manual muscle testing of at least 2/5 in 3 or more muscle groups in affected upper limb Exclusion Criteria: 1. Active neck pain, headaches, or vertigo limiting ability to tolerate Virtual Reality Head Mounted Device 2. Patients with hemicraniectomy 3. Current uncontrolled seizures 4. Active infections requiring contact precautions 5. Cognitively unable to participate 6. Vision loss limiting ability to participate with VR therapy |
Outcome
Primary Outcome Measures
1. Motor Activity Log [Change in score (between baseline and time of discharge from rehabilitation hospital, about 2 weeks)]
Secondary Outcome Measures
1. Modified Barthel's Index [Change in score (between baseline and time of discharge from rehabilitation hospital, about 2 weeks)]
2. Fugl-Meyer Upper Extremity Assessment [Change in score (between baseline and time of discharge from rehabilitation hospital, about 2 weeks)]
3. Montreal Cognitive Assessment [Change in score (between baseline and time of discharge from rehabilitation hospital, about 2 weeks)]
4. Functional Independence Measurement Score [Change in score (between baseline and time of discharge from rehabilitation hospital, about 2 weeks)]
