Safety and Prevention of OveRTraining
Keywords
Abstract
Description
A total number of 15 elite-level runners (both male and female) and 80-100 soccer players (both male and female) will participate in the study.The day when participants (runners) will arrive at the lab early in the morning, after an overnight fast. They will have their blood pressure and orthostatic heart rate measured and they will also provide a blood sample. Immediately after participants' body composition will be assessed by dual energy X-ray absorptiometry (DXA). Then, they will perform the Meeusen test providing a second blood sample immediately after the test. During the subsequent 4-hour resting period, the participants followed by assessment of joint mobility, delayed onset of muscle soreness, flexibility and vertical jump performance after that lower limb peak torque by isokinetic dynamometer. A second Meeusen test will take place after the resting period with blood sampling post-testing. Then, participants will have a 3-hour rest, after which they will visit the lab again in order to perform the running economy testing protocol and a maximal lactate steady state test. Finally, participants will complete POMS-, quality of sleep- and symptomatology-related questionnaires and will be taught on how to complete dietary recalls. Over the subsequent 12-month period participants will provide the investigator with a detailed report of their training plan and a symptomatology questionnaire every month. These measurements take place for all participants in two different periods, in transitional period/baseline and in middle season (berore tha main race). If someone of participants manifest the symptoms of overtraining, they perform the protocol of measurements again. The day when participants (soccer players) will arrive at the lab early in the morning, after an overnight fast. They will have their blood pressure and orthostatic heart rate measured and they will also provide a blood sample. Immediately after participants' body composition will be assessed by dual energy X-ray absorptiometry (DXA). The participants followed by assessment of joint mobility, delayed onset of muscle soreness, flexibility and vertical jump performance after that lower limb peak torque by isokinetic dynamometer. After resting, they will measurement the maximum oxygen uptake in stress test on the aisle. The next days, in football players take place in field tests, will measure the Speed in 10, 30 meters, Yo-Yo IE2 (Intermittent Endurance 2), Yo-Yo IR2 (Intermittent Recovery 2) and Repeated Sprint Ability (RSA). Finally, participants (soccer players) will complete POMS-, quality of sleep- and symptomatology-related questionnaires and will be taught on how to complete dietary recalls.These measurements take place for all participants in two different periods, in transitional period/baseline and in middle season (berore tha main race). If someone of participants manifest the symptoms of overtraining, they perform the protocol again.
Dates
Last Verified: | 11/30/2019 |
First Submitted: | 06/04/2018 |
Estimated Enrollment Submitted: | 02/05/2019 |
First Posted: | 02/06/2019 |
Last Update Submitted: | 12/25/2019 |
Last Update Posted: | 12/26/2019 |
Actual Study Start Date: | 12/31/2017 |
Estimated Primary Completion Date: | 05/31/2020 |
Estimated Study Completion Date: | 07/29/2020 |
Condition or disease
Intervention/treatment
Behavioral: Overtraining Monitoring
Phase
Arm Groups
Arm | Intervention/treatment |
---|---|
Runners Long-distance runners, marathon runners, 5 km and 10 km runners, both female and male aged 20 - 40 years, participating in regular training and competitions. | |
Soccer Players High Level soccer players, both female and male aged 15-30, participating in all games |
Eligibility Criteria
Ages Eligible for Study | 15 Years To 15 Years |
Sexes Eligible for Study | All |
Sampling method | Probability Sample |
Accepts Healthy Volunteers | Yes |
Criteria | Inclusion Criteria for Runners: Participants: - should be long-distance runners, marathon runners, 5 km and 10 km runners. - should be able to provide the daily training plan and a 7-day dietary recall every month. - should be considered elite level runners. - should be free of musculoskeletal injuries for at least one year before the study. Inclusion Criteria for Soccer Players: Participants: - should be elite soccer players. - should be able to provide the daily training plan and a 7-day dietary recall. - should be participated in matches. - should be free of musculoskeletal injuries for at least one year before the study. Exclusion Criteria (both Runners and Soccer Players): If participants: - do not adhere to rules of the study. - have a recent history of illness or injury . - do not participate in competitive training. |
Outcome
Primary Outcome Measures
1. Change in cell free plasma DNA [At baseline, at six months and at twelve months]
2. Change in Cortisol level [At baseline, at six months and at twelve months]
3. Change in Testosterone level [At baseline, at six months and at twelve months]
4. Change in cytokine response [At baseline, at six months and at twelve months]
5. Change in creatine kinase in plasma [At baseline, at six months and at twelve months]
6. Change in uric acid in plasma [At baseline, at six months and at twelve months]
7. Change in protein carbonyls in blood [At baseline, at six months and at twelve months]
8. Change in total antioxidant capacity [At baseline, at six months and at twelve months]
9. Change in reduced glutathione in blood [At baseline, at six months and at twelve months]
10. Change in oxidized glutathione in blood [At baseline, at six months and at twelve months]
11. Change in catalase activity [At baseline, at six months and at twelve months]
12. Change in malondialdehyde in blood [At baseline, at six months and at twelve months]
Secondary Outcome Measures
1. Change in blood lactate concentration [At baseline, at six months and at twelve months]
2. Change in peak torque [At baseline, at six months and at twelve months]
3. Change in orthostatic heart rate. [At baseline, at six months and at twelve months]
4. Change in jumping ability. [At baseline, at six months and at twelve months]
5. Change in flexibility [At baseline, at six months and at twelve months]
6. Change in body composition. [At baseline, at six months and at twelve months]
7. Change in delay onset of muscle soreness (DOMS) [At baseline, at six months and at twelve months]
8. Change in complete blood count [At baseline, at six months and at twelve months]
9. Change in RSA [At baseline, at six months and at twelve months]
10. Change in Yo-Yo IE2 [At baseline, at six months and at twelve months]
11. Change in Yo-Yo IR2 [At baseline, at six months and at twelve months]
12. Change in Spreed [At baseline, at six months and at twelve months]
13. Dietary intake [At baseline, at six months and at twelve months]
14. Change in jumping ability. [At baseline, at six months and at twelve months]
15. Change in jumping ability. [At baseline, at six months and at twelve months]