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International Journal of Psychiatry in Medicine 2007

A case with euprolactinemic galactorrhea induced by escitalopram.

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Murat Gulsun
Ayhan Algul
Umit Basar Semiz
Mehmet Alpay Ates
Ali Doruk
Servet Ebrinc
Cengiz Basoglu
Mesut Cetin

Keywords

Abstract

Endocrine and reproductive side effects of serotonergic antidepressants are uncommon and galactorrhea is only rarely mentioned among SSRI-related side effects. Perhaps through suppression of dopamine neurotransmission releasing prolactin from tonic inhibitor control of dopamine, serotonin-enhancing antidepressants may result in a rise in prolactin levels. However, we here describe a case of euprolactinemic galactorrhea induced by the SSRI escitalopram and discuss potential mechanisms of action.

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