Journal of Natural Products 2003-Jul

Cytotoxic diterpenes from Scoparia dulcis.

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Monira Ahsan

S K N Islam

Alexander I Gray

William H Stimson

ARTICLE: 12880314

DOI: 10.1021/np020356j

BioSeek: 12880314

Keywords

Abstract

Four new labdane-derived diterpenes, iso-dulcinol (1), 4-epi-scopadulcic acid B (2), dulcidiol (4), and scopanolal (5), together with two known diterpenes, dulcinol/scopadulciol (3) and scopadiol (6), were isolated from the aerial parts of Scoparia dulcis. The structures were determined by extensive NMR studies. The crude extracts as well as the pure diterpenes showed cytotoxicity against a panel of six human stomach cancer cell lines.

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Cytotoxic diterpenes from Scoparia dulcis.

Keywords

scopadulcic acid b

diterpene

stomach neoplasms

neoplasms

scoparia

scoparia dulcis

Abstract

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