[Effect of obzidan on coronary blood flow in patients with the hyperkinetic type of hemodynamics in the acute period of myocardial infarct].

Changes in the rate of coronary venous flow through the affected area under the effect of intravenous jet injections of propranolol, 0.1 mg per 1 kg body weight, were assessed in 18 patients of the hyperkinetic central hemodynamic type during acute myocardial infarction. In the first group of patients, whose mean flow rate through the affected wall was 106.2 +/- 5.7 ml/min, the latter parameter decreased in proportion to the drop in double product. In the second group of patients, whose coronary venous flow rate was reduced (51.4 +/- 6.9 ml/min), propranolol-induced drop in the flow rate was less marked, as compared to the drop in double product. It was correlated with dramatically depressed pumping function of the heart.