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Fitoterapia 2013-Oct

Four new diterpenes from Aphanamixis polystachya.

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Hai-Feng Wu
Xiao-Po Zhang
Ying Wang
Jing-Yi Zhang
Guo-Xu Ma
Yu Tian
Li-Zhen Wu
Shi-Lin Chen
Jun-Shan Yang
Xu-Dong Xu

Keywords

Abstract

Four novel diterpenes possessing rare five-membered peroxide ring, aphanaperoxides E-H (1-4), were isolated from stem bark of Aphanamixis polystachya. Their structures including the absolute configuration were elucidated by spectroscopic data and CD analysis. The cytotoxicities of the isolated compounds against a panel of human cancer cell lines were evaluated.

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