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Giornale Italiano di Cardiologia 2013-Jun

[Herbs and cardiotoxic effects].

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Stefano Maffè
Paola Paffoni
Maria Laura Colombo
Franca Davanzo
Pierfranco Dellavesa
Lorenzo Cucchi
Franco Zenone
Anna Maria Paino
Nicolò Franchetti Pardo
Luca Bergamasco

Keywords

Abstract

Accidental or deliberate ingestion of poisonous herbs has become an increasingly common phenomenon over the last years. From existing literature data and case reports from emergency room visits or poison control centers, an overview is presented of the potential cardiotoxic manifestations following intoxication by wild herbal plants of the territory. The effects of the consumption of cardiac glycoside-containing plants (e.g., digitalis) are discussed along with tachyarrhythmias induced by Aconitum napellus L., Atropa belladonna L., Mandragora officinarum L. or Ephedra distachya L. herbs, and hypertensive crises associated with licorice abuse. For each plant, a brief historical and botanical background is provided, focusing on pathophysiology of intoxication and cardiotoxic effects on the basis of the most recent literature. Finally, medical management of intoxication, from both a general and cardiological viewpoint, is reviewed.

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