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Ocular Immunology and Inflammation 2012-Dec

Optic disc neovascularization revealing neurosyphilis.

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F Trechot
T Maalouf
P Kaminsky
K Angioi

Keywords

Abstract

OBJECTIVE

To report a case of neurosyphilis revealed by bilateral optic disc neovascularization.

METHODS

Case report.

METHODS

A 39-year-old man presented with a 6-month history of progressive visual loss (20/25 RE, 20/1200 LE) and transient headaches. Fundus examination demonstrated a 1+ vitritis, mild macular edema and large optic disc neovascularization in both eyes. Serological tests for syphilis were positive.

RESULTS

Specific antibiotics and systemic steroids were undertaken and complete regression of disc neovascularization was observed within 6 months.

CONCLUSIONS

Optic disc neovascularization, which is a rare manifestation of chronic uveitis, may lead to the diagnosis of neurosyphilis and be successfully treated by specific antibiotic and steroid therapy.

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