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American Journal of Ophthalmology 2018-Sep

Residual iris retraction syndrome after artificial iris implantation.

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Christian S Mayer
Andrea E Laubichler
Michael Masyk
Philipp Prahs
Daniel Zapp
Ramin Khoramnia

Keywords

Abstract

OBJECTIVE

To evaluate the effect of an artificial iris implant on the remnant iris.

METHODS

Interventional case series METHODS: Setting: single-centre PATIENT POPULATION: 42 consecutive patients OBSERVATION PROCEDURES: Morphological evaluation over 24±14 months MAIN OUTCOME MEASURES: Remnant pupillary aperture, iris colour, visual acuity, intraocular pressure and endothelial cell count.

RESULTS

In 7 of 42 cases (16.7%), the residual iris aperture dilated from 36.6±15.4 mm2 preoperatively to 61.1±12.5 mm2 one year postoperatively (66.9% increase). In 5 of 7 affected eyes the artificial iris had been implanted into the ciliary sulcus, in 2 eyes it had been sutured to the sclera. 4 of the 7 patients presented with remarkable complications: 2 eyes needed glaucoma shunt surgeries due to pigment dispersion; 1 suffered from recurrent bleedings and in 1 case artificial iris explantation was performed due to chronic inflammation. Anterior chamber depth and angle, endothelial cell count and visual acuity did not change in this cohort. Changes in color were not observed in the remnant iris.

CONCLUSIONS

The implantation of an artificial iris prosthesis can lead to a residual iris retraction syndrome. It is likely that residual iris is trapped in the fissure between the artificial iris and the anterior chamber angle, preventing further pupil constriction. Another possibility could be a constriction or atrophy of the residual iris. A scleral-sutured implant or an implantation in the capsular bag were both found to prevent the iris retraction. The study group number is inadequate to allow statistical comparison of these different implantation methods. As the use of artificial irises increases, we may expect more patients with iris retraction syndrome in the future.

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