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Fitoterapia 2014-Apr

Steroidal saponins from dragon's blood of Dracaena cambodiana.

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Hai-Yan Shen
Wen-Jian Zuo
Hui Wang
You-Xing Zhao
Zhi-Kai Guo
Ying Luo
Xiao-Na Li
Hao-Fu Dai
Wen-Li Mei

Keywords

Abstract

Six new steroidal saponins, cambodianosides A-F (1-6), together with seven known ones, were isolated from the dragon's blood of Dracaena cambodiana. The structures of 1-6 were elucidated on the basis of detailed spectroscopic analysis, including 1D and 2D NMR techniques and chemical methods. The cytotoxicities of all the isolated compounds were evaluated in vitro against three human cancer cell lines, and compounds 7, 8, and 11 showed significant inhibitory activities.

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