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Phytotherapy Research 2004-Apr

Trypanocidal activity of chemical constituents from Lychnophora salicifolia Mart.

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Christiane Oliveira Jordão
Walter Vichnewski
Glória Emília Petto de Souza
Sérgio Albuquerque
João Luis Callegari Lopes

Keywords

Abstract

The ethyl acetate extract from leaves plus inflorescences of L. salicifolia showed significant trypanocidal activity against trypomastigote forms of T. cruzi, which was due to the flavonoid quercetin-7,3',4'-trimethyl ether and the sesquiterpenoid lychnopholic acid. Despite the use of some species of Lychnophora in folk medicine for pain relief, crude extracts from L. salicifolia Mart. showed no antinociceptive activity in the mouse writhing test.

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