Journal of Physiology 2018-Nov
Ventilatory and integrated physiological responses to chronic hypercapnia in goats.
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Keywords
Abstract
CONCLUSIONS
Chronic hypercapnia per se has distinct effects on the mechanisms regulating steady-state ventilation and the CO2 /H+ chemoreflex. Chronic hypercapnia leads to sustained hyperpnoea that exceeds predicted ventilation based upon the CO2 /H+ chemoreflex. There is an integrative ventilatory, cardiovascular and metabolic physiological response to chronic hypercapnia. Chronic hypercapnia leads to deterioration of cognitive function.
UNASSIGNED
I and the CO2 /H+ chemoreflex, and (2) deterioration of cognitive function.
