amorpha canescens/melanoma

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Tyrosinase Inhibition and Kinetic Details of Puerol A Having But-2-Enolide Structure from Amorpha fruticosa

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Puerol A (1) from Amorpha fruticosa showed highly potent inhibition against both monophenolase (IC₅₀ = 2.2 μM) and diphenolase (IC₅₀ = 3.8 μM) of tyrosinase. We tried to obtain a full story of enzyme inhibitory behavior for inhibitor 1 because the

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