androsace foliosa/cytochrome c

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Saxifragifolin B from Androsace umbellata induced apoptosis on human hepatoma cells.

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Bioassay-guided phytochemical study of Androsace umbellata led to the successful isolation of saxifragifolin B (SB) for the first time. The anti-tumor effect of SB was firstly reported that it was shown to have potent cytotoxicity on human hepatoma HepG2 cells with IC50 value of 11.9 microM at 24 h.

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