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anoectochilus annamensis/phosphatase
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3 results
Potent protein tyrosine phosphatase 1B (PTP1B) inhibiting constituents from Anoectochilus chapaensis and molecular docking studies.
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BACKGROUND
Anoectochilus chapaensis Gagnep. (Orchidaceae), an indigenous and valuable Chinese folk medicine, has been used as an antidiabetic remedy. However, the bioactive constituents have not been reported.
OBJECTIVE
To explore potent protein tyrosine phosphatase 1B (PTP1B) inhibitors from the
Ameliorative effects of Anoectochilus formosanus extract on osteopenia in ovariectomized rats.
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The purpose of this study was to determine ameliorative effects of crude aqueous extract of Anoectochilus formosanus (AFE) on osteopenia in ovariectomized (OVX) rats. First, all of the rats were divided into sham and OVX groups. The OVX rats were allowed to lose bone for 6 weeks. At 6 weeks
Kinsenoside prevents ovariectomy-induced bone loss and suppresses osteoclastogenesis by regulating classical NF-κB pathways.
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Kinsenoside is able to improve bone turnover rate in ovariectomized (OVX) mice. In vitro analysis shows that kinsenoside antagonizes osteoclast development and bone resorption.
BACKGROUND
Kinsenoside, the main active compound of the traditional Taiwanese herb Anoectochilus formosanus, has an
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