arthralgia/atrophy

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Overexpression of MMPs, cytokines, and RANKL/OPG in temporomandibular joint osteoarthritis and their association with joint pain, mouth opening, and bone degeneration. A preliminary report

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Objective: This study aimed to determine the expression of distinct matrix metalloproteinases, cytokines, and bone-resorptive factors in temporomandibular joint osteoarthritis (TMJ-OA) patients and their association with joint pain, mouth

High molecular weight hyaluronic acid relieved joint pain and prevented the progression of cartilage degeneration in a rabbit osteoarthritis model after onset of arthritis.

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We examined the therapeutic effect of high molecular weight hyaluronic acid (HA) on the progression of joint pain and cartilage degeneration in a rabbit osteoarthritis (OA) model. The OA model was induced by partial meniscectomy. In the time course study, cartilage degeneration was assessed at 3, 7

Subchondral bone changes and the impacts on joint pain and articular cartilage degeneration in osteoarthritis.

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Subchondral bone has received increasing attention in both basic and clinical research on osteoarthritis (OA). Subchondral bone in OA presents abnormalities in structure, biochemical composition, biomechanics and cellular function. Overall, subchondral bone mainly shows bone resorption in early OA

Cartilage degeneration is associated with augmented chemically-induced joint pain in rats: a pilot study.

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BACKGROUND Osteoarthritis arising from cartilage degeneration is the most common cause of joint pain. However, the relationship between joint pain and cartilage degeneration is not well understood. OBJECTIVE We asked whether the inflammatory mediators participate in the joint pain in the presence of

Magnetic resonance imaging (MRI)-defined cartilage degeneration and joint pain are associated with poor physical function in knee osteoarthritis - the Oulu Knee Osteoarthritis study.

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The main aim was to investigate the associations between Magnetic Resonance Imaging (MRI)-defined structural pathologies of the knee and physical function. A cohort study with frequency matching on age and sex with eighty symptomatic subjects with knee pain and suspicion or diagnosis of knee

Hemifacial atrophy and temporomandibular joint pain-dysfunction syndrome.

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A case is described of a patient with progressive HA who presented because of left TMJ pain, jaw locking and ipsilateral masticatory muscle spasm. Several reports exist in the literature of masticatory muscle spasm associated with HA. A diagnosis of TMJPDS was made and an occlusal splint was

[Skin pigmentation deposits, hypertrichosis of the forearms and thighs, arthralgia of the knee, edema of the posterior of the legs, bloating, muscular atrophy and general weakness (bone radiography)--craniotomy for the treatment of arachnoiditis of the optic chiasm: (multiple myeloma)].

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Spinal muscular atrophy associated with progressive myoclonic epilepsy is caused by mutations in ASAH1.

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Spinal muscular atrophy (SMA) is a clinically and genetically heterogeneous disease characterized by the degeneration of lower motor neurons. The most frequent form is linked to mutations in SMN1. Childhood SMA associated with progressive myoclonic epilepsy (SMA-PME) has been reported as a rare

Evaluation of the Effect of Mega MSM on Improving Joint Function in Populations Experiencing Joint Degeneration.

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Joint degeneration has become a commonplace problem in aging populations. The main clinical manifestations include joint pain, joint stiffness and joint swelling with functional disorder. Mega MSM is a nutritional supplement that may provide potential relief for joint problems associated with joint

Acute temporomandibular joint pain-dysfunction syndrome: neuro-otologic and electromyographic study.

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To test the hypothesis that the acute temporomandibular joint pain-dysfunction syndrome might represent a variant of acute benign cranial polyneuritis, a prospective study was designed using neuro-otologic examination and electromyography. Seven consecutive patients with cardinal symptoms of the

Is radiosynovectomy (RS) effective for joints damaged by haemophilia with articular degeneration in simple radiography (ADSR)?

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BACKGROUND Radiosynovectomy (RS) is known to be effective in the treatment of chronic haemophiliac synovitis. Its effectiveness may, however, be different when the joint treated shows articular degeneration in simple radiography (ADSR). OBJECTIVE The purpose of this study was to investigate the

Trajectories of physical functioning and their prognostic indicators: a prospective cohort study in older adults with joint pain and comorbidity.

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OBJECTIVE This study aimed to identify and characterize homogeneous subgroups of individuals with distinct trajectories of physical functioning (PF) and to examine prognostic indicators of deterioration in PF in a highly heterogeneous population of older adults with joint pain and

Efficacy of magnetic resonance imaging with an SPGR sequence for the early evaluation of knee cartilage degeneration and the relationship between cartilage and other tissues.

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The aim of this study was to investigate the efficacy of magnetic resonance imaging (MRI) with a spoiled gradient-recalled (SPGR) sequence to evaluate early knee cartilage degeneration and the relationship between cartilage and other tissues using a modified Whole-Organ Magnetic

Temporomandibular joint degeneration in Alport's syndrome: review of literature and case report.

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A case of Alport's syndrome and coincidental temporomandibular joint degenerative disease is reported. Alport's syndrome is an unusual genetic disease that ultimately results in renal failure and has a high incidence of sensorineural hearing loss. The patient presented had complaints of facial and

Osteoarthropathy of hepatolenticular degeneration.

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Ninety-six joints of 25 patients with hepatolenticular degeneration have been studied by means of scintigraphs with technetium (99mTc), a method which can disclose early synovial inflammation and postinflammatory articular degeneration. Signs of synovitis were found in 22 joints of 10 patients (40%)

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