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Page 1 from 63 results
Immortalized human microglia cell line
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RESEARCH SUPPORT
The research for the present invention was supported in part by grants from the Multiple Sclerosis Society of Canada and the Canadian Myelin Research Initiative.
FIELD OF THE INVENTION
The present invention is concerned generally with glial cell components of the central nervous
Movement disorder therapy system, devices and methods, and intelligent methods of tuning
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BACKGROUND OF THE INVENTION
(1) Field of the Invention
The present invention relates to therapeutic medical apparatus systems, delivery systems, devices and/or methods, and to apparatus and methods for using neural stimulation to alleviate the symptoms of movement disorders, such as those associated
Movement disorder therapy system, devices and methods, and intelligent methods of tuning
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BACKGROUND OF THE INVENTION
(1) Field of the Invention
The present invention relates to therapeutic medical apparatus systems, delivery systems, devices and/or methods, and to apparatus and methods for using neural stimulation to alleviate the symptoms of movement disorders, such as those associated
Movement disorder therapy system, devices and methods, and intelligent methods of tuning
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BACKGROUND OF THE INVENTION
(1) Field of the Invention
The present invention relates to therapeutic medical apparatus systems, delivery systems, devices and/or methods, and to apparatus and methods for using neural stimulation to alleviate the symptoms of movement disorders, such as those associated
Human I.kappa.B-.beta.
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FIELD OF INVENTION
This invention relates to newly identified polynucleotides, polypeptides encoded by them and to the use of such polynucleotides and polypeptides, and to their production. More particularly, the polynucleotides and polypeptides of the present invention relate to the I.kappa.B
Intranasal compositions
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CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a Section 371 of International Application No. PCT/GB2004/005446, filed Dec. 23, 2004, which was published in the English language on Jul. 7, 2005, under International Publication No. WO 2005/060945 A2 and the disclosure of which is
Inhibitors of transcription factor-NF-.kappa.B
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FIELD OF THE INVENTION
This invention relates in general to salicylanilide inhibitors of transcription factor NF-.kappa.B. Such compounds are particularly useful for treating diseases in which activation of NF-.kappa.B is implicated. More specifically, these compounds inhibit I.kappa.B
Movement disorder therapy system and methods of tuning remotely, intelligently and/or automatically
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BACKGROUND OF THE INVENTION
(1) Field of the Invention
The present invention relates to therapeutic medical apparatus systems, delivery systems, devices and/or methods, and to apparatus and methods for using neural stimulation to alleviate the symptoms of movement disorders, such as those associated
Movement disorder therapy system and methods of tuning remotely, intelligently and/or automatically
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BACKGROUND OF THE INVENTION
(1) Field of the Invention
The present invention relates to therapeutic medical apparatus systems, delivery systems, devices and/or methods, and to apparatus and methods for using neural stimulation to alleviate the symptoms of movement disorders, such as those associated
Movement disorder therapy system, devices and methods, and methods of remotely tuning
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BACKGROUND OF THE INVENTION
(1) Field of the Invention
The present invention relates to therapeutic medical apparatus systems, delivery systems, devices and/or methods, and to apparatus and methods for using neural stimulation to alleviate the symptoms of movement disorders, such as those associated
Movement disorder therapy system and methods of tuning remotely, intelligently and/or automatically
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BACKGROUND OF THE INVENTION
(1) Field of the Invention
The present invention relates to therapeutic medical apparatus systems, delivery systems, devices and/or methods, and to apparatus and methods for using neural stimulation to alleviate the symptoms of movement disorders, such as those associated
Induced expression of brain derived neurotrophic factor (BDNF) for treatment of Neuromuscular, neurodegenerative, autoimmune, developmental and/or metabolic diseases
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BACKGROUND OF THE INVENTION
Brain-derived neurotrophic factor (BDNF) is one of several endogenous proteins that play key roles in neuronal development. BDNF influences nerve growth as a neurotrophin and/or as a myokine. Therefore there is a need for improved methods for inducing expression of BDNF.
Induced expression of brain derived neurotrophic factor (BDNF) for treatment of neuromuscular, neurodegenerative, autoimmune, developmental and/or metabolic diseases
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BACKGROUND OF THE INVENTION
Brain-derived neurotrophic factor (BDNF) is one of several endogenous proteins that play key roles in neuronal development. BDNF influences nerve growth as a neurotrophin and/or as a myokine. Therefore there is a need for improved methods for inducing expression of BDNF.
Induced expression of brain derived neurotrophic factor (BDNF) for treatment of neuromuscular, neurodegenerative, autoimmune, developmental and/or metabolic diseases
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BACKGROUND OF THE INVENTION
Brain-derived neurotrophic factor (BDNF) is one of several endogenous proteins that play key roles in neuronal development. BDNF influences nerve growth as a neurotrophin and/or as a myokine. Therefore there is a need for improved methods for inducing expression of BDNF.
Activators of class I histone deacetlyases (HDACs) and uses thereof
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FIELD OF THE INVENTION
The field of the invention pertains to activators of class I histone deacetylases and their uses in the treatment of neurological disorders.
BACKGROUND OF THE INVENTION
In a variety of neurodegenerative disorders such as ischemia and Alzheimer's disease (Hayashi et al.,
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