The aim of the present study was to investigate, in vivo, the effect of a Brugmansia arborea extract (BRU), chromatographic fractions (FA and FNA), and isolated alkaloids on the expression and the acquisition of morphine tolerance and dependence. Substances were acutely (for expression) or
Traditional medicine is a primary source for the study of medicinal plants. In some countries, knowledge about the therapeutic use of medicinal plants is very deep and very often 'magical' plants also are used to diagnose and treat illnesses. The study of these plants can help in the research of
This study describes 32 fungal endophytes isolated from different tissues of Brugmansia aurea Lagerh. Each fungal strain was authenticated based on internal transcribed spacer rDNA sequence. Phylogenetic analysis showed that these fungi are distributed in three classes, seven orders and 12 genera.
The tropane alkaloid anisodamine ( 2) is obtained by 6 beta-hydroxylation of hyoscyamine ( 1). The application of this alkaloid in medicine is gaining attention due to the wide range of therapeutic applications described in addition to its anticholinergic activity. In this work, the production of
BACKGROUND
Ethno medicinal traditional knowledge regarding the uses of indigenous medicinal plants for treating various human infectious diseases is totally in hold of the elder community members. The young generation is not much aware about such vital traditional medicinal practices.
OBJECTIVE
To
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