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butyl acetate/inflammation
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5 results
The local anti-inflammatory activity of rimexolone (Org 6216) in fibrin-induced monoarticular arthritis and adjuvant-induced arthritis.
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The effects of a number of steroids administered intra-articularly in a chronic model of fibrin-induced monoarticular arthritis in the rabbit have been investigated. Org 6216 hydrocortisone acetate, prednisolone tertiary butyl acetate and triamcinolone hexacetonide each suppressed the joint swelling
Development of a new formulation of roflumilast for pulmonary drug delivery to treat inflammatory lung conditions.
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The aim of this study was to develop roflumilast dry powder inhaler (DPI) formulations by spray drying using hydroxypropyl-β-cyclodextrin (HPβCD) and to determine their suitability for pulmonary delivery. Different feed solution concentrations, solvent systems and spray drying parameters were used
Preparative enantioseparation of loxoprofen precursor by recycling countercurrent chromatography with hydroxypropyl-β-cyclodextrin as a chiral selector.
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Recycling countercurrent chromatography was successfully applied to the resolution of 2-(4-bromomethylphenyl)propionic acid, a key synthetic intermediate for synthesis of nonsteroidal anti-inflammatory drug loxoprofen, using hydroxypropyl-β-cyclodextrin as chiral selector. The two-phase solvent
Intraarticular corticosteroids in treatment of osteoarthritis.
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The history of the use of intraarticular corticosteroids in the treatment of osteoarthritis and the various available corticosteroid preparations, their possible mechanism of action, side effects, and results of treatment are presented. The longest-lasting effects in the alleviation of joint
Sensory irritation as a basis for setting occupational exposure limits.
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There is a need of guidance on how local irritancy data should be incorporated into risk assessment procedures, particularly with respect to the derivation of occupational exposure limits (OELs). Therefore, a board of experts from German committees in charge of the derivation of OELs discussed the
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