1-Deoxynojirimycin (DNJ, C₆H13NO₄, 163.17 g/mol), an alkaloid azasugar or iminosugar, is a biologically active natural compound that exists in mulberry leaves and Commelina communis (dayflower) as well as from several bacterial strains such as Bacillus and Streptomyces species. Deoxynojirimycin
The antiviral activity of total alkaloids from Commelina communis L. (TAC) against influenza virus A/PR/8/34 (H1N1) was investigated in vitro and in vivo. TAC exhibited an inhibitory action on the growth of influenza virus in Madin-Darby canine kidney cells when added before or after viral
We have previously examined the antiviral effects of total alkaloids from Commelina communis L. (TAC). Here we investigated the active constituents of TAC, responsible for the antiviral effect. Harman, homonojirimycin (HNJ) and 2,5-dihydroxymethyl-3,4-dihydroxypyrrolidine were isolated from TAC by
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