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3 results
Reversal of tall larkspur (Delphinium barbeyi) poisoning in cattle with physostigmine.
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Tall larkspur poisoning of cattle is a serious problem on western US rangelands. Single oral doses of tall larkspur ranging from 1.5 to 3 g/kg body weight were administered to steers. These doses caused clinical signs of muscular tremors and collapse. Physostigmine was administered iv, ip or sc at
Effect of α₇ nicotinic acetylcholine receptor agonists and antagonists on motor function in mice.
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Nicotinic acetylcholine receptors (nAChRs) are ligand-gated cation channels found throughout the body, and serve to mediate diverse physiological functions. Muscle-type nAChRs located in the motor endplate region of muscle fibers play an integral role in muscle contraction and thus motor function.
Practical toxicologic diagnosis.
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Strychnine toxicosis is characterized by inducible tetanic seizures and metaldehyde poisoning by fine fasciculations progressing to generalized tremors and seizures. Intoxication with 1080 causes seizures, random running movements, vomiting, defecation, urination, acidosis and hyperglycemia.
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