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cyanocobalamin/breast neoplasms

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Methotrexate-induced myelopathy responsive to substitution of multiple folate metabolites.

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Methotrexate (MTX)-associated myelopathy is a rare but serious subacute complication of MTX-based chemotherapy. We report the case of a woman with breast cancer and meningeal carcinomatosis who developed severe progressive myelopathy after four cycles of intrathecal MTX administration. We

Slow-targeted release of a ruthenium anticancer agent from vitamin B12 functionalized marine diatom microalgae.

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Herein we report the synthesis of a new biomaterial designed for targeted delivery of poorly water-soluble inorganic anticancer drugs, with a focus on colorectal cancer. Diatomaceous earth microparticles derived from marine microalgae were coated with vitamin B12 (cyanocobalamin) as a tumor
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