cycas/lung neoplasms

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Sotetsuflavone inhibits proliferation and induces apoptosis of A549 cells through ROS-mediated mitochondrial-dependent pathway.

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BACKGROUND Sotetsuflavone is isolated from Cycas revoluta Thunb., which has biological activity against tumors. However, the anti-proliferative effects of sotetsuflavone on A549 cells and its mechanism are not fully elucidated. METHODS This study investigated the mechanisms of growth inhibition,

Extract of Cycas revoluta Thunb. enhances the inhibitory effect of 5-ﬂuorouracil on gastric cancer cells through the AKT-mTOR pathway.

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BACKGROUND

Gastric cancer is one of the most common and deadly malignancies worldwide. Despite recent medical progress, the 5-year survival rate of gastric cancer is still unsatisfactory. 5-ﬂuorouracil (5-Fu) is one of the first-line antineoplastic treatments for gastric cancer,

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