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dihydrotanshinone/atrophy

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ArticlesClinical trialsPatents
3 results

[Dihydrotanshinone I (DHTS1) attenuates cuprizone-induced demyelination via regulating microglia polarization]

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Objective To evaluate whether dihydrotanshinone I (DHTS1) attenuates cuprizone-induced demyelination. Methods DHTS1 was dissolved in 5 g/L sodium carboxymethyl cellulose (CMC-Na). The cuprizone model was induced via feeding with the diet containing 2 g/L cuprizone. We administrated DHTS1 to the

Inhibition of C1-Ten PTPase activity reduces insulin resistance through IRS-1 and AMPK pathways.

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Insulin resistance causes type 2 diabetes; therefore, increasing insulin sensitivity is a therapeutic approach against type 2 diabetes. Activating AMP-activated protein kinase (AMPK) is an effective approach for treating diabetes, and reduced insulin receptor substrate-1 (IRS-1) protein levels have

Novel diterpenoid acetylcholinesterase inhibitors from Salvia miltiorhiza.

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Acetylcholinesterase (AChE, EC 3.1.1.7) inhibitors are the only registered drugs used to treat Alzheimer's disease (AD). New AChE inhibitors may contribute to the design of new pharmaceuticals and supply information which will facilitate the understanding of the interaction between inhibitors and
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