fanconi anemia/areca

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Areca nut induces miR-23a and inhibits repair of DNA double-strand breaks by targeting FANCG.

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Previous investigations have shown that areca nut extracts (ANE) or arecoline (ARE) causes DNA damage, which in turn contributes to oral cell carcinogenesis. To understand the role of microRNA (miRNA) in ANE-associated carcinogenesis, miRNA expression profile was examined in ANE-treated normal human

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