fever/obesity

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Uncoupling protein 4 (UCP-4)

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FIELD OF THE INVENTION A novel uncoupling protein, which we have designated UCP-4, that is expressed in various tissues, including brain, heart, pancreas, and muscle tissue, and nucleic acid molecules which encode said novel protein, are described. Methods of screening for compounds that regulate

Methods of using GPR101 receptors to identify modulators of hypothalamic proopiomelanocortin (POMC)-derived biologically active peptide secretion

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FIELD OF THE INVENTION The present invention relates to methods of using GPR101 G protein-coupled receptor (GPCR) to screen candidate compounds as modulators of hypothalamic proopiomelanocortin (POMC)-derived biologically active peptide secretion. Modulators of GPR101 receptor modulate hypothalamic

Compound WS 727713

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TECHNICAL FIELD The present invention relates to a new compound which is useful as a medicament or a cosmetic, to a process for producing the same and to a pharmaceutical composition comprising the same. BACKGROUND ART The melanocortin (MC) is a group of peptide hormones that are derived from

Modulation of substance P by compounds containing calcium sulfate and methods relating thereto

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TECHNICAL FIELD The present invention relates generally to a method of modulating substance P by compounds containing calcium sulfate, particularly syngenite, gorgeyite and gypsum, and more specifically, to the synthesis of such compounds as well as their use to treat a variety of conditions

Substituted pyrido[2,3-d]pyrimidines as delta-5-desaturase inhibitors

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CROSS-REFERENCE TO RELATED APPLICATIONS This application is a U.S. national stage of International Application No. PCT/JP2011/066766 filed Jul. 22, 2011. TECHNICAL FIELD The present invention relates to a novel fused heterocyclic compound having superior properties as a medicament, and use thereof.

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