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fibrocystic breast disease/albumin

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Characteristics of cystic breast disease with special regard to breast cancer development.

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BACKGROUND This prospective study compares the characteristics of cystic disease of the breast (CDB) of patients who developed breast cancer (BCa) during the follow-up (1.25-4 years) period with those who did not. METHODS K+, Na+, albumin, dehydroepiandrosterone (DHA), DHA-sulphate, oestrone,

Cyst fluid proteases.

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The precise origin of breast cyst fluid remains obscure. Molina has presented evidence that type II cysts (high Na/K ratio) may be transudative, that is, partly derived from plasma elements which enter through gap junctions, while Type I cysts (high K/Na ratio) are primarily secretory. In

Proteases in cyst fluid from human gross cyst breast disease.

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Cyst fluid from women with gross cystic breast disease was found to contain protease activity when assayed against [14C]albumin. At least six different proteases were detected when the fluid was fractionated by a combination of S-300 Sephacel, hydroxylapatite, and DEAE-Sephacel chromatographic
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