flueggea suffruticosa/leukemia

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Virosecurinine induces apoptosis in human leukemia THP-1 cells and other underlying molecular mechanisms.

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Virosecurinine, a primary alkaloid from Securinega suffruticosa plant is known as a potent differentiation-inducing agent in acute leukemia cells. The present study aimed to investigate the effects and underlying mechanisms of virosecurinine on human leukemia THP-1 cells in vitro. The effects of

Induction of human chronic myeloid leukemia K562 cell apoptosis by virosecurinine and its molecular mechanism.

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Virosecurinine is a major alkaloid of the plant Securinega suffruticosa and has been found to be a potent agent in inducing the differentiation of cancer cells. The present study aimed to investigate the antitumor effects of virosecurinine by inducing the apoptosis of leukemic K562 cells and to

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