Bioassay-guided fractionation of the EtOH extract of the stem bark of Funtumia elastica resulted in the isolation of four steroidal alkaloids, holarrhetine (1), conessine (2), holarrhesine (3) and isoconessimine (4). Their structures were determined on the basis of 1D- and 2D-NMR techniques and mass
BACKGROUND
Funtumia elastica (Preuss) Stapf. (Apocynaceae) has a long ethnopharmacological history for uses such as treatment of whooping cough, asthma, blennorhea, painful menstruation, fungal infections, and wounds.
OBJECTIVE
To investigate the antimicrobial and anti-inflammatory properties of
The study of Apocynaceae species used in traditional medicine reveals that 25 species in 16 genera are of ethnobotanical interest. Nineteen species are medicinal, sixteen of which fall under the subfamily Plumerioideae which usually has indole alkaloids. The most common category of diseases treated
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