galactorrhea/protease

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Galactorrhoea and hyperprolactinaemia associated with protease-inhibitors.

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We describe four patients with galactorrhoea as an isolated endocrine abnormality after use of protease inhibitors (PIs) as part of both highly active antiretroviral therapy (HAART) and postexposure prophylaxis (PEP). This reaction may be a direct effect of PIs or may be indirectly mediated by the

Galactorrhoea, hyperprolactinaemia, and protease inhibitors.

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Galactorrhoea, hyperprolactinaemia, and protease inhibitors.

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Galactorrhoea, hyperprolactinaemia, and protease inhibitors.

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Galactorrhoea, hyperprolactinaemia, and protease inhibitors.

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Ritonavir and Saquinavir directly stimulate anterior pituitary prolactin secretion, in vitro.

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An association between human immunodeficiency virus type I (HIV-1) protease inhibitors (PIs) and galactorrhoea/hyperprolactinemia adverse effect has recently been reported in four HIV-1-infected women treated with PIs (indinavir, nelfinavir, ritonavir or saquinavir). This could be explained by a

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