galactorrhea/seizures

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Reproductive dysfunction in women with epilepsy: menstrual cycle abnormalities, fertility, and polycystic ovary syndrome.

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Epilepsy can be associated with reproductive endocrine disorders. In women these include polycystic ovary syndrome (PCOS), isolated components of this syndrome such as polycystic ovaries or hyperandrogenemia, hypothalamic amenorrhea (HA), or functional hyperprolactinemia (HPRL). The most likely

[Reports of suspected side effects of selective serotonin reuptake inhibitors in Belgium and The Netherlands].

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OBJECTIVE To study the adverse drug reaction (ADR) profile of selective serotonin re-uptake inhibitors (SSRI) in Belgium and the Netherlands. METHODS Descriptive study. METHODS The Belgian Pharmacovigilance Centre and the Dutch Drug Safety Unit. METHODS All adverse reactions of fluoxetine,

Massive breast enlargement in an infant girl with central nervous system dysfunction.

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A 6-month-old female is described who presented with severe idiopathic macromastia. The breast enlargement began at 2 months of age and progressed such that subtotal mastectomies were necessary at 23 months. Extensive hormonal evaluation prior to surgery revealed no evidence of estrogenization or

Bromocriptine

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Bromocriptine is usually not used during breastfeeding because it suppresses lactation. The indication of lactation suppression has been withdrawn in the U.S. and discouraged in other countries because it increases the risk of maternal stroke, seizures, cardiovascular disorders, death and possibly

Reproductive dysfunction in women with epilepsy: recommendations for evaluation and management.

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BACKGROUND Epilepsy is commonly associated with reproductive endocrine disorders. These include polycystic ovary syndrome (PCOS), isolated components of this syndrome such as polycystic ovaries, hyperandrogenaemia, hypothalamic amenorrhoea, and functional hyperprolactinaemia. OBJECTIVE To summarise

No unexpected adverse events and biochemical side effects of olanzapine as adjunct treatment in adolescent girls with eating disorders.

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OBJECTIVE Olanzapine has been recently tried to relieve anxiety and hyperactivity in adolescents with eating disorders (EDs). Presently, the side effects of the drug have been evaluated. METHODS Forty-seven adolescents with EDs were followed up by repeated blood sampling before, during, and at 3

Thrombotic thrombocytopenic purpura associated with a prolactin-producing pituitary adenoma.

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We report here the case of a 44-year-old woman with thrombocytopenia, anemia, convulsions, hyperprolactinemia, and galactorrhea. The patient died of cardiac failure. Autopsy revealed PAS-positive and von Willebrand factor-positive microthrombi in the arterioles and capillaries of many organs, mainly

Pregnancy outcome in pituitary tumors.

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OBJECTIVE To observe the maternal and perinatal outcome in pituitary tumor (macro- and micro-adenoma) during pregnancy. METHODS A retrospective analysis of a total of 19 cases of pituitary tumor group 1 (10 macroadenoma), and group 2 (9 microadenoma), during pregnancy over last 3 years in our unit

Adverse reactions of selective serotonin reuptake inhibitors: reports from a spontaneous reporting system.

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OBJECTIVE The selective serotonin (5-hydroxytryptamine; 5-HT) reuptake inhibitors (SSRIs) are extensively used in the treatment of depression, panic disorder and obsessive-compulsive disorder, and are now being evaluated in the treatment of a number of other psychiatric disorders. The aim of this

Atypical antipsychotics and pituitary tumors: a pharmacovigilance study.

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OBJECTIVE To analyze the disproportionality of reporting of hyperprolactinemia, galactorrhea, and pituitary tumors with seven widely used antipsychotic drugs. METHODS Retrospective pharmacovigilance study. METHODS United States Food and Drug Administration's Adverse Event Reporting System (AERS)

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