hardwickiic acid/neoplasms

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Biological Activities and Cytotoxicity of Eperua oleifera Ducke Oil-resin.

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UNASSIGNED The oil-resin of Eperua oleifera Ducke has been used in popular medicine similarly to the copaiba oil (Copaifera spp.). UNASSIGNED This study aimed to investigate the effects of the acid fraction of E. oleifera oil-resin (AFEOR) on cell proliferation, collagen production in human

A chemical proteomics approach reveals Hsp27 as a target for proapoptotic clerodane diterpenes.

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Clerodane diterpenoids are a class of naturally occurring molecules widely distributed in the Lamiaceae family. Neo-clerodane diterpenoids from Salvia ssp were recently described as compounds inhibiting the proliferation of human cancer cell lines. To gain new insights into molecular mechanism(s)

Biological activities and cytotoxicity of diterpenes from Copaifera spp. Oleoresins.

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Copaifera spp. are Amazonian species widely studied and whose oleoresins are used by local people for various medicinal purposes. However, a detailed study of the activity of the main phytochemical components of these oleoresins remains to be done. Here, we studied the cytotoxicity and in vitro

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