Although gene transfer to hematopoietic stem cells (HSCs) has shown therapeutic efficacy in recent trials for several individuals with inherited disorders, transduction incompleteness of the HSC population remains a hurdle to yield a cure for all patients with reasonably low integrated vector
Despite the fact that 59% of people living with HIV (PLHIV) currently achieve viral suppression on antiretroviral therapy (ART), recent gains in controlling the global HIV/AIDS epidemic may be threatened: key HIV incidence rates are declining only modestly, the sustainability of programs to expand
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