hymenocardia/malaria

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In Vitro and In Vivo Study of the Gastrointestinal Absorption and Metabolisation of Hymenocardine, a Cyclopeptide Alkaloid.

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Hymenocardine is a cyclopeptide alkaloid present in the root bark of Hymenocardia acida. In traditional African medicine, the leaves and roots of this plant are used to treat malaria, and moderate in vitro antiplasmodial activity has been reported for hymenocardine. However, in view of its

In vitro antiplasmodial activity and cytotoxicity of ethnobotanically selected Ivorian plants.

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Eight extracts from four Ivorian medicinal plants, traditionally used to treat malaria, were tested for their antiplasmodial activity in vitro by assessing their ability to inhibit the uptake of [3H]hypoxanthine into the Plasmodium falciparum K1 chloroquine-resistant strain. The most active extract

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