intermittent claudication/hemorrhage

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[High blood pressure as cause of intermittent claudication and cerebral hemorrhage].

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Hemorrhagic lumbar facet cysts accompanying a spinal subdural hematoma at the same level.

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BACKGROUND We present a rare and interesting case of hemorrhagic lumbar facet cysts accompanying a spinal subdural hematoma at the same level suggesting a possible mechanism by which spinal subdural hematomas can arise. RESULTS A 71-year-old man presented with persistent sciatic pain and

Lethal hemorrhage caused by aortoenteric fistula following endovascular stent implantation.

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A 55-year-old women developed an aortointestinal fistula between the bifurcation of the aorta and the distal ileum following implantation of multiple endovascular stents into both common iliac arteries for treatment of aortoiliac occlusive disease. Ten months before the acute onset of the

Interspinous process implantation for the treatment of neurogenic intermittent claudication.

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BACKGROUND Lumbar spinal stenosis (LSS) is a disabling medical condition in which narrowing of the spinal canal compresses the spinal cord and nerves causing a condition called neurogenic intermittent claudication (NIC). Decompressive spine surgery is the standard of care for patients who fail to

Managing PAD with multiple platelet inhibitors: the effect of combination therapy on bleeding time.

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OBJECTIVE Patients with lower-extremity peripheral arterial disease (PAD) face a high risk of cardiovascular morbidity and mortality. Platelet inhibition (PI) significantly reduces this risk. Combination PI is common and increasingly indicated in patients with PAD; however, the effect on platelet

Cilostazol: new drug. Intermittent claudication: too little efficacy, too many risks.

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(1) Intermittent claudication is usually a sign of generalised vascular atheroma, with prognosis mainly depending on the degree of coronary and cerebral involvement. Treatment is based on smoking cessation and regular exercise. Vasodilators have a purely symptomatic effect, modest at best, in

[Protective effects of cilostazol against transient focal cerebral ischemia and hemorrhagic transformation].

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Cilostazol, a selective inhibitor of phosphodiesterase III, is an antiplatelet drug and a vasodilator via increased cAMP levels. It has been approved for the treatment of ischemic symptoms in chronic peripheral arterial obstruction or intermittent claudication and for secondary prevention of

Variability in responsiveness to clopidogrel in patients with intermittent claudication.

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OBJECTIVE The concept of clopidogrel resistance is frequently evoked in the cardiac literature. The variability of antiplatelet response in patients with intermittent claudication has not been investigated. The aim of this study was to describe the effect of the addition of clopidogrel to aspirin

Acenocoumarol and pentoxifylline in intermittent claudication. A controlled clinical study. The APIC Study Group.

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The efficacy and safety of pentoxifylline (400 mg tid orally) and acenocoumarol, administered singly or in combination, in the treatment of intermittent claudication associated with chronic occlusive arterial disease were evaluated in a multi-center, randomized, factorial, blind clinical trial

Efficacy of low-molecular-weight heparin in the management of intermittent claudication.

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Treating chronic arterial occlusive disease with heparin is controversial because of the risks associated with long-term anticoagulant therapy. Low molecular weight (LMW) heparin (mw about 5000 Dalton), which selectively inhibits the Xa factor with minimal risk of hemorrhage, seems to offer new

Risk, types, and severity of intracranial hemorrhage in patients with symptomatic carotid artery stenosis.

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OBJECTIVE We sought to report the occurrence and risk factors of intracranial hemorrhage during long-term follow-up of patients with internal carotid artery stenosis, with and without carotid endarterectomy. METHODS From the prospective data of the North American Symptomatic Carotid Endarterectomy

Lack of effect of a 24-hour infusion of iloprost in intermittent claudication.

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24 hour infusion of iloprost was compared with placebo infusion in 19 patients with stable intermittent claudication using a double blind, balanced crossover design. Despite significant inhibition of platelet aggregation to ADP and collagen (p less than 0.001) and the typical cardiovascular and

Clinical efficacy of picotamide in long-term treatment of intermittent claudication.

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The clinical efficacy of picotamide was investigated in a randomized, double-blind, placebo-controlled study in patients with peripheral occlusive arterial disease of the lower limbs at functional stage II of the Fontaine classification. Forty patients with a history of claudication for at least six

The effect of a combined administration of ridogrel and ketanserin in patients with intermittent claudication.

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After a 1-month placebo run-in phase, 27 patients with proven peripheral arterial obstructive disease participated in a double blind placebo controlled study and were divided in 3 groups, receiving either placebo, ridogrel 300 mg b.i.d. (a combined thromboxane synthase and receptor blocking agent)

Efficacy of cilostazol after endovascular therapy for femoropopliteal artery disease in patients with intermittent claudication.

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OBJECTIVE The purpose of this study was to investigate whether cilostazol reduces restenosis and revascularization after endovascular therapy (EVT) for femoropopliteal lesions. BACKGROUND Cilostazol improves walking distance in patients with intermittent claudication and reduces restenosis after

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