iris sanguinea/obesity

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PTP1B inhibitors from the seeds of Iris sanguinea and their insulin mimetic activities via AMPK and ACC phosphorylation.

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To find PTP1B inhibitors from natural products, two new compounds (1 and 2), along with nine known compounds (3-11), were isolated from a methanol-soluble extract of Iris sanguinea seeds. The structures of compounds 1 and 2 were determined based on extensive spectroscopic data analysis including UV,

[The influence of effective treatment of diabetes mellitus and obesity on the plasma concentration of immunoreactive insulin].

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A study was made of 16 patients with the initial mild form of diabetes mellitus in whom the immunoreactive insulin (IRI) indices in glucose loading pointed to a good reactivity of the beta-cells of the insular apparatus of the pancreas. As a result of the dietetic treatment or therapy with

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