Three iridals, iridotectorals A and B, and iridobelamal. A, were isolated from rhizomes of Iris tectorum and Belamcanda chinensis, respectively, along with five known iridals. Their structures were elucidated on the basis of spectral evidence. The human promyelocytic leukemia (HL-60) cell-adhesion
Thirteen species of Iridaceae plants were studied with the capability to induce HL-60 promyelocytic leukemia cells into macrophages. The neutrophil stimulating activity in these plants was also examined by measuring superoxide production. Both activities are known to be possessed by tumor promoters
A spiroiridal-type triterpenoid, 28-deacetylbelamcandal (1), was isolated from the rhizomes of Iris tectorum as an active principle that stimulated differentiation of human promyelocytic leukemia (HL-60) cells, a short-term screening method for 12-O-tetradecanoylphorbol 13-acetate (TPA)-type tumor
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