iris tectorum/neoplasms

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Protein kinase C activation by iridal type triterpenoids.

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Eleven iridal type triterpenoids from Iris tectorum and Belamcanda chinensis were examined for protein kinase C (PKC) activation and binding activity to PKC. Among the tested compounds, nine iridals showed dose-dependent activities, and a mutual relation between the two activities was also observed.

[Study of iridaceae plants with the capability to induce differentiation of HL-60 promyelocytic leukemia cells].

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Thirteen species of Iridaceae plants were studied with the capability to induce HL-60 promyelocytic leukemia cells into macrophages. The neutrophil stimulating activity in these plants was also examined by measuring superoxide production. Both activities are known to be possessed by tumor promoters

The sulphorhodamine (SRB) assay and other approaches to testing plant extracts and derived compounds for activities related to reputed anticancer activity.

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Since the major approach in searching for potential anticancer agents over the last 50 years has been based on selective cytotoxic effects on mammalian cancer cell lines, cell-based methods for cytotoxicity are described and compared. The sulphorhodamine B (SRB) assay is described in detail as the

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