iris/infarction

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IRIS-BVS AMI Registry

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IRIS : Use of Implantable Defibrillator in High-risk Patients Early After Acute Myocardial Infarction

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Remote Ischemic Conditioning in ST-elevation Myocardial Infarction as Adjuvant to Primary Angioplasty

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Ischemic heart disease (IHD) is the leading cause of mortality worldwide, accounting for over 7 million deaths per year. ST-elevation myocardial infarction (STEMI) accounts for nearly one third of acute coronary syndromes. Despite improved STEMI patient care achieved mainly by timely primary

Effects of Melatonin on Reperfusion Injury

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Nitrite Infusion in High Risk Patients Undergoing Cardiopulmonary Bypass

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Acute kidney injury is one of the most untoward consequences of cardiac-surgery with the use of CPB. As such it is associated with a high mortality and morbidity and health care expense. Unfortunately, currently, there is no effective preventive or treatment strategy for cardiac surgery-associated

Trial of Nonsurgical Treatment of Intermittent Claudication Due to Femoro-popliteal Disease

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Intermittent claudication (IC) is a common problem in the UK's elderly population with a prevalence of 5 -10%. Intermittent claudication infers significant quality of life limitations, however, it is a disease which generally runs a benign course with >80% of patients remaining stable. Yet the

Familial Hypercholesterolemia Amongst Patients With Acute Coronary Syndrome

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Familial hypercholesterolemia (FH) is a genetic disorder, defines as high cholesterol levels, particularly very high levels of low-density lipoprotein (LDL), in the blood and early cardiovascular events and premature death. FH is an autosomal dominant disease with a prevalence of 1:500 (new study in

The Acute and Chronic Effects of Remote Ischemic Conditioning on Cardiovascular Function

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The present study is a prospective, randomized trial conducted at the Second University Department of Cardiology in Attikon University Hospital. A two hundred seventy patients with STEMI , within 48 hours after primary PCI are randomized in two remote conditioning (RIC) protocols or no intervention

Efficacy Study of Lucentis in the Treatment of Diabetic Macular Edema

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Diabetic macular edema (DME) results from abnormal leakage of macromolecules into the extracellular space from microaneurysms and incompetent blood vessel walls due to small vessel damage from high blood glucose levels. Oncotic forces then allow water into the extracellular space. Abnormalities in

Analysis of Clinical Profiles of Chinese Patients With Normal Tension Glaucoma

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This is a multi-centered non-interventional descriptive study. The Declaration of Helsinki is followed. All procedures will be conducted in accordance with the GCP guidelines. About 100 Consecutive NTG glaucoma patients will be included in this study. NTG is defined as: 1. Six median untreated

2000 HIV Human Functional Genomics Partnership Program

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Study population: A cohort with a total of 2000 HIV patients will be built, consisting of a discovery cohort (n=1200) and confirmation cohort (n=800). The investigators estimate a 2-year inclusion and 2-year follow-up period and will strive for the inclusion of several clinical phenotypes such as

Adjunctive Corticosteroids for Tuberculous Meningitis in HIV-infected Adults (The ACT HIV Trial)

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Mycobacterium tuberculosis causes ~9 million new cases of tuberculosis and ~1.5 million deaths annually, around 0.4 million of whom are co-infected with HIV. Tuberculous meningitis (TBM) is the most severe form of tuberculosis, killing around 30% of all sufferers despite appropriate

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